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Universiteit Leiden

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2010

van Beers, M.M., Sauerborn, M., Gilli, F., Brinks, V., Schellekens, H., Jiskoot, W. , Aggregated Recombinant Human Interferon Beta Induces Antibodies but No Memory in Immune-Tolerant Transgenic Mice, Pharm Res.

Hagenaars, N., Mania, M., de Jong, P., Que, I, Nieuwland, R., Slutter, B., Glansbeek, H., Heldens, J., van den Bosch, H., Lowik, C., Kaijzel, E., Mastrobattista, E., Jiskoot, W. , Role of trimethylated chitosan (TMC) in nasal residence time, local distribution and toxicity of an intranasal influenza vaccine, J Control Release, vol. 144, no. 1, pp. 17-24.

Filipe, V., Hawe, A., Jiskoot, W. , Critical evaluation of Nanoparticle Tracking Analysis (NTA) by NanoSight for the measurement of nanoparticles and protein aggregates, Pharm Res, vol. 27, no. 5, pp. 796-810.

Carpenter, J.F., Randolph, T.W., Jiskoot, W., Crommelin, D.J., Middaugh, C.R., Winter, G. , Potential inaccurate quantitation and sizing of protein aggregates by size exclusion chromatography: essential need to use orthogonal methods to assure the quality of therapeutic protein products, J Pharm Sci, vol. 99, no. 5, pp. 2200-8.

Rasmussen, T., Tantipolphan, R., van de Weert, M., Jiskoot, W. , The Molecular Chaperone alpha-Crystallin as an Excipient in an Insulin Formulation, Pharm Res.

Bal, S.M., Slutter, B., van Riet, E., Kruithof, A.C., Ding, Z., Kersten, G.F., Jiskoot, W., Bouwstra, J.A. , Efficient induction of immune responses through intradermal vaccination with N-trimethyl chitosan containing antigen formulations, J Control Release, vol. 142, no. 3, pp. 374-83.

Ding, Z., Bal, S.M., Romeijn, S., Kersten, G.F., Jiskoot, W., Bouwstra, J.A. , Transcutaneous Immunization Studies in Mice Using Diphtheria Toxoid-Loaded Vesicle Formulations and a Microneedle Array, Pharm Res.

Groen, D., Gooris, G.S., Bouwstra, J.A. , Model membranes prepared with ceramide EOS, cholesterol and free fatty acids form a unique lamellar phase, Langmuir, vol. 26, no. 6, pp. 4168-75.

Ackaert, O.W., De Graan, J., Capancioni, R., Della Pasqua, O.E., Dijkstra, D., Westerink, B.H., Danhof, M., Bouwstra, J.A. , The in vitro and in vivo evaluation of new synthesized prodrugs of 5-OH-DPAT for iontophoretic delivery, J Control Release.

Tantipolphan, R., Romeijn, S., Engelsman, J., Torosantucci, R., Rasmussen, T., Jiskoot, W. , Elution behavior of insulin on high-performance size exclusion chromatography at neutral pH, J Pharm Biomed Anal, vol. 52, no. 2, pp. 195-202.

Hawe, A., Poole, R., Jiskoot, W. , Misconceptions over Forster resonance energy transfer between proteins and ANS/bis-ANS: Direct excitation dominates dye fluorescence, Anal Biochem, vol. 401, no. 1, pp. 99-106.

Amidi, M., Mastrobattista, E., Jiskoot, W., Hennink, W.E. , Chitosan-based delivery systems for protein therapeutics and antigens, Adv Drug Deliv Rev, vol. 62, no. 1, pp. 59-82.

van Beers, M.M., Sauerborn, M., Gilli, F., Hermeling, S., Brinks, V., Schellekens, H., Jiskoot, W. , Hybrid transgenic immune tolerant mouse model for assessing the breaking of B cell tolerance by human interferon beta, J Immunol Methods, vol. 352, no. 1-2, pp. 32-7.

Thakoersing, V.S., Ponec, M., Bouwstra, J.A. , Generation of Human Skin Equivalents Under Submerged Conditions-Mimicking the In Utero Environment, Tissue Eng Part A.

Slutter, B., Soema, P.C., Ding, Z., Verheul, R., Hennink, W., Jiskoot, W. , Conjugation of ovalbumin to trimethyl chitosan improves immunogenicity of the antigen, J Control Release.

Ackaert, O.W., Van Smeden, J., De Graan, J., Dijkstra, D., Danhof, M., Bouwstra, J.A. , Mechanistic Studies of the Transdermal Iontophoretic Delivery of 5-OH-DPAT In Vitro, Journal of Pharmaceutical Sciences, vol. 99, no. 1, pp. 275-285.

Ackaert, O.W., Eikelenboom, J., Wolff, H.M., Bouwstra, J.A. , Comparing different salt forms of rotigotine to improve transdermal iontophoretic delivery, Eur J Pharm Biopharm, vol. 74, no. 2, pp. 304-10.

Hawe, A., Filipe, V., Jiskoot, W. , Fluorescent molecular rotors as dyes to characterize polysorbate-containing IgG formulations, Pharm Res, vol. 27, no. 2, pp. 314-26.

Sauerborn, M., Brinks, V., Jiskoot, W., Schellekens, H. , Immunological mechanism underlying the immune response to recombinant human protein therapeutics, Trends Pharmacol Sci, vol. 31, no. 2, pp. 53-9.

Marsden, H.R., Quer, C.B., Sanchez, E.Y., Gabrielli, L., Jiskoot, W., Kros, A. , Detergent-aided polymersome preparation, Biomacromolecules, vol. 11, no. 4, pp. 833-8.

2009

Hawe, A., Kasper, J.C., Friess, W., Jiskoot, W. , Structural properties of monoclonal antibody aggregates induced by freeze-thawing and thermal stress, European Journal of Pharmaceutical Sciences, vol. 38, no. 2, pp. 79-87.

Slutter, B., Plapied, L., Fievez, V., Sande, M.A., des Rieux, A., Schneider, Y.J., Van Riet, E., Jiskoot, W., Preat, V. , Mechanistic study of the adjuvant effect of biodegradable nanoparticles in mucosal vaccination, J Control Release, vol. 138, no. 2, pp. 113-21.

Rissmann, R., Oudshoorn, M.H., Hennink, W.E., Ponec, M., Bouwstra, J.A. , Skin barrier disruption by acetone: observations in a hairless mouse skin model, Arch Dermatol Res, vol. 301, no. 8, pp. 609-13.

Rasmussen, T., Kasimova, M.R., Jiskoot, W., van de Weert, M. , The Chaperone-like Protein alpha-Crystallin Dissociates Insulin Dimers and Hexamers, Biochemistry, vol. 48, no. 39, pp. 9297-9304.

Groen, D., Gooris, G.S., Bouwstra, J.A. , New insights into the stratum corneum lipid organization by X-ray diffraction analysis, Biophys J, vol. 97, no. 8, pp. 2242-9.

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